The gut microbiome in human neurological disease: A review.
Identifieur interne : 000011 ( Main/Exploration ); précédent : 000010; suivant : 000012The gut microbiome in human neurological disease: A review.
Auteurs : Helen Tremlett [Canada] ; Kylynda C. Bauer [Canada] ; Silke Appel-Cresswell [Canada] ; Brett B. Finlay [Canada] ; Emmanuelle Waubant [États-Unis]Source :
- Annals of neurology [ 1531-8249 ] ; 2017.
Abstract
Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses. These microorganisms collectively form the human microbiota, with most colonizing the gut. Recent technological advances, open access data libraries, and application of high-throughput sequencing have allowed these microbes to be identified and their contribution to neurological health to be examined. Emerging evidence links perturbations in the gut microbiota to neurological disease, including disease risk, activity, and progression. This review provides an overview of the recent advances in microbiome research in relation to neuro(auto)immune and neurodegenerative conditions affecting humans, such as multiple sclerosis, neuromyelitis optica spectrum disorders, Parkinson disease, Alzheimer disease, Huntington disease, and amyotrophic lateral sclerosis. Study design and terminology used in this rapidly evolving, highly multidisciplinary field are summarized to empower and engage the neurology community in this "newly discovered organ." Ann Neurol 2017;81:369-382.
DOI: 10.1002/ana.24901
PubMed: 28220542
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000042
- to stream PubMed, to step Curation: 000042
- to stream PubMed, to step Checkpoint: 000042
- to stream Ncbi, to step Merge: 002226
- to stream Ncbi, to step Curation: 002226
- to stream Ncbi, to step Checkpoint: 002226
- to stream Main, to step Merge: 000011
- to stream Main, to step Curation: 000011
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The gut microbiome in human neurological disease: A review.</title>
<author><name sortKey="Tremlett, Helen" sort="Tremlett, Helen" uniqKey="Tremlett H" first="Helen" last="Tremlett">Helen Tremlett</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bauer, Kylynda C" sort="Bauer, Kylynda C" uniqKey="Bauer K" first="Kylynda C" last="Bauer">Kylynda C. Bauer</name>
<affiliation wicri:level="1"><nlm:affiliation>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Appel Cresswell, Silke" sort="Appel Cresswell, Silke" uniqKey="Appel Cresswell S" first="Silke" last="Appel-Cresswell">Silke Appel-Cresswell</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Finlay, Brett B" sort="Finlay, Brett B" uniqKey="Finlay B" first="Brett B" last="Finlay">Brett B. Finlay</name>
<affiliation wicri:level="1"><nlm:affiliation>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waubant, Emmanuelle" sort="Waubant, Emmanuelle" uniqKey="Waubant E" first="Emmanuelle" last="Waubant">Emmanuelle Waubant</name>
<affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>University of California, San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28220542</idno>
<idno type="pmid">28220542</idno>
<idno type="doi">10.1002/ana.24901</idno>
<idno type="wicri:Area/PubMed/Corpus">000042</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000042</idno>
<idno type="wicri:Area/PubMed/Curation">000042</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000042</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000042</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000042</idno>
<idno type="wicri:Area/Ncbi/Merge">002226</idno>
<idno type="wicri:Area/Ncbi/Curation">002226</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002226</idno>
<idno type="wicri:Area/Main/Merge">000011</idno>
<idno type="wicri:Area/Main/Curation">000011</idno>
<idno type="wicri:Area/Main/Exploration">000011</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The gut microbiome in human neurological disease: A review.</title>
<author><name sortKey="Tremlett, Helen" sort="Tremlett, Helen" uniqKey="Tremlett H" first="Helen" last="Tremlett">Helen Tremlett</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bauer, Kylynda C" sort="Bauer, Kylynda C" uniqKey="Bauer K" first="Kylynda C" last="Bauer">Kylynda C. Bauer</name>
<affiliation wicri:level="1"><nlm:affiliation>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Appel Cresswell, Silke" sort="Appel Cresswell, Silke" uniqKey="Appel Cresswell S" first="Silke" last="Appel-Cresswell">Silke Appel-Cresswell</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Faculty of Medicine (Neurology) and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Finlay, Brett B" sort="Finlay, Brett B" uniqKey="Finlay B" first="Brett B" last="Finlay">Brett B. Finlay</name>
<affiliation wicri:level="1"><nlm:affiliation>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waubant, Emmanuelle" sort="Waubant, Emmanuelle" uniqKey="Waubant E" first="Emmanuelle" last="Waubant">Emmanuelle Waubant</name>
<affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>University of California, San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Annals of neurology</title>
<idno type="eISSN">1531-8249</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses. These microorganisms collectively form the human microbiota, with most colonizing the gut. Recent technological advances, open access data libraries, and application of high-throughput sequencing have allowed these microbes to be identified and their contribution to neurological health to be examined. Emerging evidence links perturbations in the gut microbiota to neurological disease, including disease risk, activity, and progression. This review provides an overview of the recent advances in microbiome research in relation to neuro(auto)immune and neurodegenerative conditions affecting humans, such as multiple sclerosis, neuromyelitis optica spectrum disorders, Parkinson disease, Alzheimer disease, Huntington disease, and amyotrophic lateral sclerosis. Study design and terminology used in this rapidly evolving, highly multidisciplinary field are summarized to empower and engage the neurology community in this "newly discovered organ." Ann Neurol 2017;81:369-382.</div>
</front>
</TEI>
<affiliations><list><country><li>Canada</li>
<li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
</list>
<tree><country name="Canada"><noRegion><name sortKey="Tremlett, Helen" sort="Tremlett, Helen" uniqKey="Tremlett H" first="Helen" last="Tremlett">Helen Tremlett</name>
</noRegion>
<name sortKey="Appel Cresswell, Silke" sort="Appel Cresswell, Silke" uniqKey="Appel Cresswell S" first="Silke" last="Appel-Cresswell">Silke Appel-Cresswell</name>
<name sortKey="Bauer, Kylynda C" sort="Bauer, Kylynda C" uniqKey="Bauer K" first="Kylynda C" last="Bauer">Kylynda C. Bauer</name>
<name sortKey="Finlay, Brett B" sort="Finlay, Brett B" uniqKey="Finlay B" first="Brett B" last="Finlay">Brett B. Finlay</name>
</country>
<country name="États-Unis"><region name="Californie"><name sortKey="Waubant, Emmanuelle" sort="Waubant, Emmanuelle" uniqKey="Waubant E" first="Emmanuelle" last="Waubant">Emmanuelle Waubant</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000011 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000011 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:28220542 |texte= The gut microbiome in human neurological disease: A review. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28220542" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonCanadaV1
This area was generated with Dilib version V0.6.29. |